INTIMATION FOR BODHIKA SEMINAR                                       15/02/2023

DEPARTMENT OF   PRASUTITANTRA AND STREEROGA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE:Dr. Gopika Raj

DISSERTATION TITLE:  COMBINED EFFECT OF CHIRUVILWADI KASHAYA WITH KANCHANARA GUGGULU IN UTERINE FIBROIDS

NAME OF GUIDE:  Dr. Shahina Mole. S MD(Ay). PhD

DATE:15/02/2023

TIME: 2:00-4:00 PM

VENUE: COLLEGE AUDITORIUM

ABSTRACT

Uterine fibroids also known as Leiomyomas are benign smooth muscle tumours of the uterus. It is predominantly an estrogen dependent tumour. It has been estimated that about 20% -80% of women develop fibroid at the age of fifty. Prevalence is highest between 35 and 45 years. Ayurveda has been able to considerably contribute to the management of fibroid. Many formulations are being effectively used in clinical practice and have been studied scientifically with proven results. Chiruvilwadi Kashaya mentioned in Sahasrayogam Arshas chikitsa and Kanchanara Guggulu mentioned in Sarngadhara Samhitha Madhyamakhanda Vatakavidhi Adhyaya is selected for the study. Uterine fibroids may be correlated to Garbhashayagatha Mamsagranthi caused by Tridosha dushti with Vatha Kapha predominance along with vitiation of Raktha, Mamsa and Medho dhatu. Hence the treatment aims at Vatha kapha hara and Medho hara action. Analyzing the dosha karma of the above formulation, easy availability and cost effectiveness of the drug ensure this medicine as a right choice. Study design is pre and post interventional with a sample size of 30. Females in the age group of 25-45 years who are diagnosed with Uterine Fibroids of size less than 8 cm will be selected from the OPD of Government Ayurveda College, Thiruvananthapuram. Women with malignancy, other chronic systemic illness, post-menopausal women, fibroid with degenerative changes, sub mucous fibroids, pregnant and lactating women and in those with Haemoglobin level less than 8g/dl will be excluded. Study tools include lab investigation, Ultrasonogram and case proforma. Patients satisfying the above criteria will be included in the study. Duration of the treatment will be 90 days and Chiruvilwadi Kashaya will be dispensed in the form of coarse powder in packets of 48 gm and Kanchanara Guggulu will be given in pill form of 1.5g each. Medicines will be dispensed on monthly basis and patients will be advised to take 48 ml of kashaya twice daily before food along with Kanchanara Guggulu 1.5g twice a day and will be reviewed after every 30 days during the study period. Outcome variables, change in size of fibroid will be assessed using USG and associated symptoms like dysmenorrhea and amount of bleeding will also be assessed. Results will be statistically analysed using Wilcoxon’s signed rank test and Paired‘t’ test according to type of distribution of variable. Results will be drawn, summarized and conclusions will be made.

NAME  OF  SECOND PRESENTEE:Dr. Mahesh Babu

DISSERTATION TITLE:  EFFECT OF KALYANAKA GHRITHAM  IN OLIGOZOOSPERMIA

NAME OF GUIDE:  Dr. Shiny. S. Raj MD (Ay)

DATE:15/02/2023

TIME: 2:00-4:00 PM

VENUE: COLLEGE AUDITORIUM

ABSTRACT

Infertility is a problem of global proportions affecting on an average of 10 to 15 % couples world wide. It is defined as not being able to conceive even after one year of regular, unprotected intercourse. Among the problems, the male factor accounts for 45-50% of causes of infertility. Oligozoospermia is a condition in which sperm concentration is less than 20 million per ml.               Oligozoospermia can be included under the Ksheenasukra in Ayurveda.

Ayurveda therapy has been widely used in the management of  male infertility as an effective, natural, safe and cost effective method and Kalyanaka ghritham is one of the formulation used for this purpose.  But these claims are not put to scientific validation. Hence  Kalyanaka Ghritham, indicated in arethasi, mentioned in Ashtangahrudayam , is taken for the study.  The study design is Pre and post interventional study with a sample size of 20  with an age group 25 to 45 years who are diagnosed as Oligozoospermia attending Infertility Clinic (OPD) of Department of Prasutitantra & Striroga, Government Ayurveda college, Thiruvananthapuram. Administration of drug is in a dose of 24 ml which is divided into two doses of 12 ml each before food. Treatment period includes 90 days intervention and 30 days observation. Assessment of this study is done with  semen analysis on 0^th day 121^st day. Results will be analyzed statistically at the end of study  with appropriate statistical method.