INTIMATION FOR BODHIKA SEMINAR - 22/06/2022

DEPARTMENTS OF SHALAKYA TANTRA   AND  RASA SHASTRA & BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ATHULYA N B

THESIS TITLE:

EFFECT OF DANTHAROGASANI CHOORNA PRATHISARRANA  AND TILAYASHTI TAILA GANDUSHA IN POST SCALING COMPLICATIONS OF DENTAL CALCULUS                                                                       

NAME OF GUIDE: Dr S SUNILKUMAR

NAME OF CO-GUIDE; Dr.AMBILI K 

DATE:22/06/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Calculus is dental plaque that has undergone mineralization. In Ayurvedic perspective,dental calculus corresponds to Danthasharkara resulting from drying up of Kapha and Mala by Vata in the oral cavity. Oral unhygienic practices are the chief aetiological factor behind the development of Danthasharkara.The treatment modality adopted was dental scaling which contribute to the increase in associated symptoms as well as some complications ,which is to be taken care after scaling.

The study was designed as an interventional pre and post evaluation without control and the sample size was fixed as 32. Patients diagnosed as having dental calculus within age group 18-60years irrespective of sex were selected from OPD and IPD of Shalakyatantra Govt. Ayurveda College, Trivandrum. The data collection was done using detailed case proforma, relevant laboratory investigations and clinical examinations. Selected patients after dental scaling were given Dantharogasani choorna Prathisarrana followed by Tilayashti taila Gandusha in a sufficient quantity for the next 30 days at morning. Plaque index, Gingival index and symptoms of Dental calculus were assessed prior to dental scaling ,after dental scaling and after treatment.The collected datas were analysed using Wilcoxon Signed Rank test and Paired t test according to the variable. Statistical analysis showed that the treatment modality is effective in managing post scaling complications of Dental calculus.

NAME  OF  SECOND PRESENTEE: Dr KEERTHANA  MADAPATTU

THESIS TITLE: 

EFFECT OF AGNIKUMARA RASA ( B.R JWARADHIKARA ) ON    STAPHYLOCOCCUS AUREUS,STREPTOCOCCUS PNEUMONIAE, KLEBSIELLA PNEUMONIAE

 – AN INVITRO STUDY                                                                   

NAME OF GUIDE: Dr  R  RAJAM

DATE:22/06/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Lower respiratory tract infections remained the most deadly communicable disease, causing 3.0 million deaths worldwide in 2016(WHO).According to Global Burden of Disease, 2015 study, Lower respiratory tract infections (LRTIs) represent 4^th most causes of death.

         Agnikumara rasa is a herbal formulation mentioned in Jwara adhikara of Bhaishajya ratnavali. It contains maricha, vacha, kusta, mustha  one part each and vatsanabha, four parts. It has the bhavana dravya of ardraka swarasa. It is indicated in amajwara, kapha jwara, pinasa, prathishaya, agnimandya, sopha, grahani, atisara, sannipatha jwara, kasa and swasa.

        The study has three parts; first is the preparation of three samples of Agnikumara rasa with reference to Bhaishajya Ratnavali jwaradhikara, with variation in the number of bhavana. ie..once, twice and quadruple times of bhavana with ardraka swarasa . Second is the physicochemical analysis of the drug and last is to check its antibacterial activity on selected lower respiratory tract infective bacteria such as staphylococcus aureus, streptococcus pneumoniae and klebsiella pneumoniae. The antibacterial study was done by the well diffusion method and Broth dilution method. It was assessed by measuring the zone of inhibition(ZIH). Triplicates of samples were done & were statistically analysed.

        It was observed that bhavana had enhanced the physico-chemical as well as quantitative parameters of all the three samples. Alcoholic extract of Agnikumara rasa of one bhavana done proved to have antibacterial activity against the three bacteria using agar-well diffusion method compared to other samples( p-value – 0.03, 0.021, 0.27 ). As satisfactory results were not obtained for other samples through this method, the study was repeated with another method, Broth dilution method. All the samples in all the three organisms showed ZIH ranging from 74 to 88 % in Staphylococcus aureus,  78 % to 89 % in Streptococcus pneumoniae, 77 % to 83 % in Klebsiella pneumoniae at 1000 µg (1 mg) concentration . All the samples of Agnikumara rasa are found to have antibacterial activity against the three bacteria and the sample with one bhavana is found to have a consistent antibacterial activity against all bacteria when statistically analysed ( two way Anova ,p-value - <0.01) . Bhavana has not reflected any change in antimicrobial property of Agnikumara rasa. Thus, Agnikumara rasa ( B.R Jwaradhikara ) has been proved with antibacterial effect on staphylococcus aureus, streptococcus pneumoniae,klebsiella pneumoniae .