INTIMATION FOR BODHIKA SEMINAR - 28/09/2022

DEPARTMENT OF RASA SHASTRA AND BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr Ranjini N R

THESIS TITLE:

ACUTE AND SUBACUTE TOXICITY OF 

RASAGARBHA POTTALI IN WISTAR RATS

NAME OF GUIDE: Dr  R. Rajam      

        

NAME OF CO-GUIDE: Dr Achuthan C R         

DATE:28/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Pottali Kalpana is a unique preparation mentioned in Ayurvedic texts. Rasagarbha pottali, the experimental drug is a formulation developed by Acharya Vasudev Mulasankara Dvivedi and Harisankar Sarma, first recorded in the book, Rasasastra by PHC Murthy. The present study was aimed at assessing the acute and sub-acute toxicity of orally administered Rasagarbha pottali. Rasagarbha Pottali was prepared in gandhaka dravapaka method. Further analyses like XRD, XRF and PSA done. Acute toxicity test was performed on Wistar rats at a single oral dose of 1000 mg/kg for 14 consecutive days. General behavioural adverse effects and mortality were determined. In the sub-acute study, Rasagarbha Pottali was administered orally at doses of 100, 150 and 200 mg/kg daily for 28 days to Wistar rats. Sections of brain, heart, lungs, livers, stomach, kidneys and reproductive organs were removed for histological studies. Acute toxicity study showed that the oral LD₅₀ value of RGP was above 1000 mg/kg. The sub-acute toxicity study did not produce any observable symptoms of toxicity and no significant variation in body weight, organ weights, haematological and biochemical parameters or mortality in all treated rats. Mercury was detected at levels below detection in the liver tissue of high-dose females via ICP-MS. It was concluded that drug RGP did not cause any systemic adverse effect in the acute and sub-acute oral toxicity trials in rats up on oral administration and is safe at all doses tested over a period of 28 days in rodents. Thus 100- 200 mg/Kg body weight of the RGP is safe to use in preclinical pharmacological efficacy analysis up to a month period.

  INTIMATION FOR BODHIKA SEMINAR - 20/09/2022

DEPARTMENT OF SAMHITA SAMSKRITA AND SIDDHANTA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr Anjitha V S

THESIS TITLE:

PREVALENCE OF IMPROPER PRACTICE OF

 AHARAVIDHIVIDHANAM IN MIGRAINE PATIENTS

NAME OF GUIDE: Dr Resmi B.MD (Ay)

NAME OF CO-GUIDE: Dr Sonia Raj S. MD (Ay)

DATE:20/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Ahara, the most essential requirement of all living beings is looked upon by Ayurveda with great relevance in the causation as well as treatment of diseases. Aharavidhividhanam are the do’s and don’ts regarding diet intake as food should be taken warm, unctuous, in due measure etc. In the present era, least importance is given to dietary rules which leads to impairment of digestive functions. Proper maintenance of digestive process depends upon ahara and method of its intake.

              Migraine is a complex, multifaceted disabling primary headache disorder often characterised by neurological, autonomic and gastrointestinal symptoms. Clinical manifestations of migraine are influenced by dietary behaviours and dietary elements. There is significant associations between Irritable Bowel syndrome, Celiac disease, GERD and Migraine. The study aims to find out the prevalence of  improper practice of aharavidhividhanam in migraine patients.

           180 cases diagnosed with migraine were selected from the OPD of Government Ayurveda college Hospital, Thiruvananthapuram. Then the prevalence of improper practice of dietetic methods was observed in migraine cases through consecutive sampling by using a validated questionnaire. Thus the observed data was statistically analysed for frequency and percentages and tested using chi-square goodness of fit test. The improper practice of aharavidhividhanam was found prevalent among migraine patients with higher prevalence to jeerne asniyat (58.88%), snigdham asniyat (58.88%), matravat asniyat (58%) and ushnam asniyat (54.44%).

  INTIMATION FOR BODHIKA SEMINAR - 14/09/2022

DEPARTMENT OF SALYA TANTRA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr MUHAMMED SAFEEQUE E K

THESIS TITLE:ADDED EFFECT OF PRACCHANA

ALONG WITH CONVENTIONAL TREATMENT

IN THE MANAGEMENT OF VICHARCHIKA

NAME OF GUIDE: Dr SHIVAKUMAR C S

 

NAME OF CO-GUIDE: Dr SREELEKHA M P

DATE:14/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Vicharchika is one among kshudrakushtha and also coming under Raktapradoshaja Vikara having involvement of three Dosha with dominance of Kapha. Lakshanas of vicharchika include kandu (itching), pidaka (papulation), syavavarna (discoloration) and lasika (oozing). Most of these features show similarity with symptoms of the disease eczema. As being a localized rakthapradoshajavikara, rakthamoksha by pracchana is an effective method of treatment in vicharchika.

The present study is designed to find out the added effect of pracchana along with conventional treatment in the management of vicharchika in reducing the signs and symptoms and to evaluate the changes in clinical and hematological parameters. The study is a comparative clinical trial. The participants were selected according to inclusion and exclusion criteria and divided into 2 groups, Group A and Group B consisting of 21 participants in each group. Both groups were given Patolakaturohinyadi kashaya 90 ml and 1 Kaishora guggulu tablet internally in morning and evening and daily kshalana of affected area is done with Thriphala kashaya for a period of 21 days. In addition to this, participants of group A were subjected with a single sitting of Pracchana in 8^th day.

Clinical assessments were done with regard to kandu, pidaka, syava and lasika. The changes in local blood parameters - TWBC, Eosinophil count, ESR, pO2 & pCO2 were analysed. The assessments were taken before and after the treatment. The data were analyzed using the most appropriate statistical tests.

The result showed that pracchana reduces kandu, shyava and lasika of vicharchika and show significant additional effect in reducing lasika and improving local blood parameters Total WBC, Eosinophil, ESR, pCO2 and pO2.

*INTIMATION REGARDING POSTPONEMENT OF BODHIKA SEMINAR*

 Respected Teachers and dear PG scholars,

 This is to inform that Bodhika Seminar series which was to be held on Wednesday i.e 7/09/22 by the dept of Salya Tantra has been postponed to next Wednesday i.e on 14/09/22 owing to the Onam celebrations in our college hospital and individual departments.

All the teachers and pg scholars are requested to be at the college auditorium for Salya Tantra bodhika seminar on 14/09/22 at 2:00 , there will be 3 presentations from the Salya Tantra dept.

  Thanking you

TEAM BODHIKA