INTIMATION FOR BODHIKA SEMINAR - 20/04/2022
DEPARTMENT OF AGADA TANTRA AND VYAVAHAR AYURVEDA
TIME: 2:00-4:00 PM
VENUE: HYBRID / MICROSOFT TEAMS
ABSTRACT
Ulcerative
colitis is a chronic inflammatory bowel disease of unknown aetiology that
results in inflammation and ulcers of colon and rectum. The primary symptoms of
active disease are abdominal pain, diarrhea mixed with blood and mucus,
tenesmus etc. and marked by alternating periods of exacerbations and remission.
Ulcerative colitis has evolved into a
global burden given its high incidence in developed countries and the
substantial increase in incidence in developing countries. In conventional
western medicine some drugs like sulfasalazine may give mild relief in symptoms
and signs but after sometime patients need more doses of the same drug. Some
patients get benefit with steroids such as prednisone which again are not
suitable because of their side-effects. Even after taking steroids and
sulfasalazine drugs patients suffer from the disease. So the patients are
always seeking some alternative therapy promising more effective and safer
outcomes.
The present study focuses on invitro
analysis of anti-inflammatory effect of Bhoonimbadi choornam in
Ulcerative colitis DLD1 colorectal cells. Bhoonimbadi choornam mentioned in the
context of visha atisara chikitsa (diarrhoea) under Vishopadrava pratisheda
adyaya in Ashtanga Samgraha uthara sthana. Atisara has long been recognized as
an important health problem in all age groups and is a major cause of morbidity
and mortality. The formulation contains
7 drugs such as Bhoonimba (Andrographis paniculata), Musta (Cyperus Rotundus), Katuka
(Picrorrhiza kurroa), Trayanti (Bacopa monnieri), Indrayava (Holarrhena
antidysenterica seed), Chitraka (Plumbago zeylanica) and Kutaja twak (Holarrhena
antidysenterica). The study evaluates the anti-inflammatory
effect of Bhoonimbadi choornam on Lipopolysaccharide activated DLD1 colorectal
cells by using inflammatory assays such as Cyclo oxygenase, Lipoxygenase, Myelo
peroxidase, Cellular nitrite and Inducible Nitric oxide synthase and results of
sample drug is compared with a standard anti-inflammatory drug Sulfasalazine
currently used in the treatment of Ulcerative colitis.
TIME: 2:00-4:00 PM
VENUE: HYBRID / MICROSOFT TEAMS
ABSTRACT
Psoriasis is recognized as the most prevalent
immune-mediated inflammatory disease, involving skin and joints and associated
with abnormalities of other systems. Palmoplantar psoriasis is a variant of psoriasis in which there are
erythematous, scaly, indurated at times fissured, plaques localized to palms
and soles. Though only small body surface area is affected but because of the
discomfort produced, this site of involvement carries a definite significance.
Palmoplantar psoriasis is such a disease which can’t be correlated exactly with
any disease mentioned in Ayurveda but to a certain extent based on its symptoms
it can be correlated with Vipadika, which is one of the type of Kshudrakushtha.
It involves predominantly Vata and Kapha dosha and characterized
by Pani-pada Sphutana(Fissure in palm and soles) and Teevra vedana
(with severe pain).
It was an interventional study with a sample size of 27 which was conducted in the OPD of Agadatantra department, Poojappura campus, Government Ayurveda college Thiruvananthapuram in the age group of 20-60 years of both sexes. Subjects satisfying inclusion criteria was selected and details were recorded as per the case proforma. The selected lepa which is prepared out of Karanja taila added with Tankana were given twice daily externally and punarnavadi kashaya 48 ml twice daily one hour before food internally for a period of 30 days. Follow up was done after 14 days. Assessment were done before treatment, after treatment and after follow up with the aid of ESFI score. Results were analysed statistically.
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