INTIMATION FOR BODHIKA SEMINAR - 28/09/2022

DEPARTMENT OF RASA SHASTRA AND BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr Ranjini N R

THESIS TITLE:

ACUTE AND SUBACUTE TOXICITY OF 

RASAGARBHA POTTALI IN WISTAR RATS

NAME OF GUIDE: Dr  R. Rajam      

        

NAME OF CO-GUIDE: Dr Achuthan C R         

DATE:28/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Pottali Kalpana is a unique preparation mentioned in Ayurvedic texts. Rasagarbha pottali, the experimental drug is a formulation developed by Acharya Vasudev Mulasankara Dvivedi and Harisankar Sarma, first recorded in the book, Rasasastra by PHC Murthy. The present study was aimed at assessing the acute and sub-acute toxicity of orally administered Rasagarbha pottali. Rasagarbha Pottali was prepared in gandhaka dravapaka method. Further analyses like XRD, XRF and PSA done. Acute toxicity test was performed on Wistar rats at a single oral dose of 1000 mg/kg for 14 consecutive days. General behavioural adverse effects and mortality were determined. In the sub-acute study, Rasagarbha Pottali was administered orally at doses of 100, 150 and 200 mg/kg daily for 28 days to Wistar rats. Sections of brain, heart, lungs, livers, stomach, kidneys and reproductive organs were removed for histological studies. Acute toxicity study showed that the oral LD₅₀ value of RGP was above 1000 mg/kg. The sub-acute toxicity study did not produce any observable symptoms of toxicity and no significant variation in body weight, organ weights, haematological and biochemical parameters or mortality in all treated rats. Mercury was detected at levels below detection in the liver tissue of high-dose females via ICP-MS. It was concluded that drug RGP did not cause any systemic adverse effect in the acute and sub-acute oral toxicity trials in rats up on oral administration and is safe at all doses tested over a period of 28 days in rodents. Thus 100- 200 mg/Kg body weight of the RGP is safe to use in preclinical pharmacological efficacy analysis up to a month period.

  INTIMATION FOR BODHIKA SEMINAR - 20/09/2022

DEPARTMENT OF SAMHITA SAMSKRITA AND SIDDHANTA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr Anjitha V S

THESIS TITLE:

PREVALENCE OF IMPROPER PRACTICE OF

 AHARAVIDHIVIDHANAM IN MIGRAINE PATIENTS

NAME OF GUIDE: Dr Resmi B.MD (Ay)

NAME OF CO-GUIDE: Dr Sonia Raj S. MD (Ay)

DATE:20/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Ahara, the most essential requirement of all living beings is looked upon by Ayurveda with great relevance in the causation as well as treatment of diseases. Aharavidhividhanam are the do’s and don’ts regarding diet intake as food should be taken warm, unctuous, in due measure etc. In the present era, least importance is given to dietary rules which leads to impairment of digestive functions. Proper maintenance of digestive process depends upon ahara and method of its intake.

              Migraine is a complex, multifaceted disabling primary headache disorder often characterised by neurological, autonomic and gastrointestinal symptoms. Clinical manifestations of migraine are influenced by dietary behaviours and dietary elements. There is significant associations between Irritable Bowel syndrome, Celiac disease, GERD and Migraine. The study aims to find out the prevalence of  improper practice of aharavidhividhanam in migraine patients.

           180 cases diagnosed with migraine were selected from the OPD of Government Ayurveda college Hospital, Thiruvananthapuram. Then the prevalence of improper practice of dietetic methods was observed in migraine cases through consecutive sampling by using a validated questionnaire. Thus the observed data was statistically analysed for frequency and percentages and tested using chi-square goodness of fit test. The improper practice of aharavidhividhanam was found prevalent among migraine patients with higher prevalence to jeerne asniyat (58.88%), snigdham asniyat (58.88%), matravat asniyat (58%) and ushnam asniyat (54.44%).

  INTIMATION FOR BODHIKA SEMINAR - 14/09/2022

DEPARTMENT OF SALYA TANTRA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr MUHAMMED SAFEEQUE E K

THESIS TITLE:ADDED EFFECT OF PRACCHANA

ALONG WITH CONVENTIONAL TREATMENT

IN THE MANAGEMENT OF VICHARCHIKA

NAME OF GUIDE: Dr SHIVAKUMAR C S

 

NAME OF CO-GUIDE: Dr SREELEKHA M P

DATE:14/09/2022

TIME: 2:00-4:00 PM

VENUE: OFFLINE AT COLLEGE AUDITORIUM

ABSTRACT

Vicharchika is one among kshudrakushtha and also coming under Raktapradoshaja Vikara having involvement of three Dosha with dominance of Kapha. Lakshanas of vicharchika include kandu (itching), pidaka (papulation), syavavarna (discoloration) and lasika (oozing). Most of these features show similarity with symptoms of the disease eczema. As being a localized rakthapradoshajavikara, rakthamoksha by pracchana is an effective method of treatment in vicharchika.

The present study is designed to find out the added effect of pracchana along with conventional treatment in the management of vicharchika in reducing the signs and symptoms and to evaluate the changes in clinical and hematological parameters. The study is a comparative clinical trial. The participants were selected according to inclusion and exclusion criteria and divided into 2 groups, Group A and Group B consisting of 21 participants in each group. Both groups were given Patolakaturohinyadi kashaya 90 ml and 1 Kaishora guggulu tablet internally in morning and evening and daily kshalana of affected area is done with Thriphala kashaya for a period of 21 days. In addition to this, participants of group A were subjected with a single sitting of Pracchana in 8^th day.

Clinical assessments were done with regard to kandu, pidaka, syava and lasika. The changes in local blood parameters - TWBC, Eosinophil count, ESR, pO2 & pCO2 were analysed. The assessments were taken before and after the treatment. The data were analyzed using the most appropriate statistical tests.

The result showed that pracchana reduces kandu, shyava and lasika of vicharchika and show significant additional effect in reducing lasika and improving local blood parameters Total WBC, Eosinophil, ESR, pCO2 and pO2.

*INTIMATION REGARDING POSTPONEMENT OF BODHIKA SEMINAR*

 Respected Teachers and dear PG scholars,

 This is to inform that Bodhika Seminar series which was to be held on Wednesday i.e 7/09/22 by the dept of Salya Tantra has been postponed to next Wednesday i.e on 14/09/22 owing to the Onam celebrations in our college hospital and individual departments.

All the teachers and pg scholars are requested to be at the college auditorium for Salya Tantra bodhika seminar on 14/09/22 at 2:00 , there will be 3 presentations from the Salya Tantra dept.

  Thanking you

TEAM BODHIKA

  INTIMATION FOR BODHIKA SEMINAR - 31/08/2022

*BODHIKA SEMINAR FOR 31/08/2022 WILL CONDUCT THREE PRESENTATIONS, 2 FROM THE DEPT OF R&B AND 1 FROM THE DEPT OF SHALYA TANTRA*

DEPARTMENT OF RASA SHASTRA & BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr RESMI BABU

THESIS TITLE:MICROBIAL STABILITY OF 

NAYOPAYAM PRAVAHI KWATHA

NAME OF GUIDE: Dr S THARALAKSHMI

DATE:31/08/2022

TIME: 2:00-4:00 PM

VENUE: COLLEGE AUDITORIUM

ABSTRACT

 Pancha vidha Kashaya kalpanas are five basic preparations of Bhaishajya kalpana.and which includes swarasa, kalka, kwatha, hima and phanta.Among them kwatha Kalpana is most significant and widely used dosage form. This is prepared by boiling of herbal drugs with water in a specific proportion .Pravahi kwatha is concentrated kashaya.It is obtained by boiling the ingredients of a specified kwatha churna formulation in a given amount of jala (API part 2 volumes 4).Addition of preservatives in pravahi kwatha is permitted as per API. Nayopayam pravahi kwatha is a decoction prepared with bala, jiraka, shunti in a ratio 10:2:2 (API Part 2 volume 4).Kwatha Kalpana has more chance to get contaminated with microbes as it is an aqueous preparation. Also during boiling of kwatha starch from drugs gets dissolved. Which provides media for the growth of micro organisms leading to its decomposition. Preservatives are used to prevent microbial contamination. As per the thesis “a study on the type and concentration of preservatives used in kwathas by the leading GMP certified companies in kerala” done in Govt. Ayurveda College, Trivandrum, it was noted that the amount of preservatives in kwatha preparation is 10 times more than the permitted limit. So, through a long-term shelf life study, an attempt was made to detect the microbial stability of Nayopayam Pravahi Kwatha with the permitted amount of preservatives using parameters such as microbial contamination, colour, odour, taste, moisture content, pH, specific gravity, and total solid content. An online survey was conducted among the GMP certified companies in kerala preparing concentrated kashayas to collect the details of preservatives in pravahi kwatha. 

 INTIMATION FOR BODHIKA SEMINAR - 24/08/2022

DEPARTMENT OF PRASOOTI TANTHRA AND STREE ROGA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr PARVATHY S

THESIS TITLE:

EFFECT OF SHILAJATU ON INSULIN RESISTANCE 

IN POLY CYSTIC OVARIAN SYNDROME

NAME OF GUIDE: Dr SHINY S RAJ

NAME OF CO-GUIDE: Dr ANILA M

DATE:24/08/2022

TIME: 2:00-3:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting reproductive aged women. It is a hyperandrogenic disorder associated with chronic oligo-anovulation and polycystic ovarian morphology. Insulin resistance and hyper androgenism are considered to be key factors in the etiology of PCOS. Obesity is known to increase circulating androgen and insulin levels, may increase PCOS prevalence and exacerbates the clinical features of PCOS. Since PCOS is an extremely common disorder, PCOS-related insulin resistance is an important cause of GDM and NIDDM  in women. In Ayurveda symptoms of PCOS are often met in diseases like Nashtartava, Artavakshaya, Pushpagni jataharini, prameha and sthoulya. The study drug is Shilajatu, which is known for its pramehagna, sthoulyahara, kaphamedohara property. In the study nineteen Females participants attending the OPD of Prasutitantra and Streeroga, Govt Ayurveda college, Thiruvananthapuram in the age group 18-38 years, fulfilling Rotterdam criteria 2003 and having insulin resistance measured as per HOMA IR value >1were selected. They were given 500mg Shilajatu, morning and evening before food for 90 days. Insulin resistance, menstrual interval, BMI, Waist to hip ratio were assessed before and after treatment. Data obtained was analysed statistically. Study drug was found to be effective in decreasing insulin resistance, reducing menstrual interval, BMI and waist to hip ratio. 

 INTIMATION FOR BODHIKA SEMINAR - 17/08/2022

DEPARTMENT OF PANCHAKARMA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

*THERE WILL BE ONLY ONE PRESENTATION ON 17TH OF AUGUST *

NAME  OF  FIRST PRESENTEE: Dr SWATHI E 

THESIS TITLE: EFFECT OF MADHUTAILIKA YAPANA VASTI IN OLIGOSPERMIA

NAME OF GUIDE: Dr MINI V G

DATE:17/08/2022

TIME: 2:00-3:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Infertility is defined as a failure to conceive within one or more years of regular unprotected coitus. According to recent report of WHO on status of infertility in India,of all infertility cases ,approximately 50% is due to male factor infertility, owing to the reproductive anomalies in the male. Oligospermia is main contributing factor in it. It is a condition of suboptimal concentration of spermatozoa in the ejaculated semen to ensure successful fertilization of an ovum. ICD 10 Code N46.1 define Oligospermia in human as a sperm count below 20 million per millimeter semen.Oligospermia can be correlated to ksheenasukra in Ayurveda. Ksheenasukra is vata-pita predominant disease. Madhutailika vasti yoga mentioned in Sharangadhara samhita is vrshya and brmhana. Hence the aim of the study was to find out the Effect of Madhutailika yapana vasti in Oligospermia. The study design was pre and post assessment interventional study with a sample size of 15 Male with an age group 25-50 years who are diagnosed having Oligospermia attending IPD of Department of Panchakarma and Department of Kayachikitsa of Govt.Ayurveda college Thiruvanthapuram. Assessment of this study was done with quantitative semen analysis. Participants were administered with Madhutailika yapana vasti for continuous 7 days. Assessment of this study was done with quantitative semen analysis. The result were analyzed with regard to changes in the outcome variable as in semen analysis. The pre and post test data was assessed with Wilcoxon signed rank test. Based on the analysis the study concludes that Madhutailika yapana vasti is effective in Oligospermia.

 INTIMATION FOR BODHIKA SEMINAR - 10/08/2022

DEPARTMENT OF KAYA CHIKITSA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ANUPAMA  A S 

THESIS TITLE: EFFECT OF AMRITA GUGGULU AND 

RASNADASAMOOLA KWATHAM IN RHEUMATOID ARTHRITIS

NAME OF GUIDE: Dr PRAVITH N K 

DATE:10/08/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown aetiology marked by a symmetric, peripheral polyarthritis. It is peaking between the ages of 35 and 50 and is a chronic disabling condition often causing pain and deformity. Clinically RA is similar to Vatarakta described in our classics. Vata prakopa and Rakta prakopa nidana leads to Raktavritha vata and lodges in Asthi sandhis. The clinical feature of Vatarakta is suggestive of deep dhathugata involvement. As it is an Avaranajanya Vyadhi, different preparations with drugs having Avaranaharatva, Vataanulomana and Rasayana properties are exclusively indicated in the management of Vatarakta. Amrita guggulu and Rasnadasamoola kwatham are two drugs having the above said qualities were selected as a combination to perform in its management.

The study was a before and after study without control group, conducted in Govt.Ayurveda College Hospital, Thiruvananthapuram. 20 patients fulfilling the inclusion and exclusion criteria diagnosed as Rheumatoid arthritis by satisfying the 2010 ACR-EULAR diagnostic criteria were selected and subjected to detailed clinical examination according to clinical research proforma and lab investigations. The study drug Amrita guggulu (500mg) twice daily with lukewarm water one hour after food and Rasnadasamoola kwatham (as sachet) with 60ml lukewarm water twice daily along with 6ml Eranda taila as anupana one hour before food  were given to the study participants for one month. Evaluation was done on 0^th and 31^st day. Statistical analysis reveals that there were significant reduction in subjective and objective parameters. Thus it is recommended that these drugs are effective and safe which can be used in the management of Rheumatoid arthritis.

 INTIMATION FOR BODHIKA SEMINAR - 03/08/2022

DEPARTMENTS OF SALYA TANTRA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr M T AMRUTHA

THESIS TITLE: EFFECT OF SELECTED  TREATMENT

 PROTOCOL IN  THE MANAGEMENT OF PARTIAL 

TEAR OF ANTERIOR CRUCIATE LIGAMENT OF 

KNEE JOINT

NAME OF GUIDE: Dr C S SIVAKUMAR

NAME OF CO-GUIDE: Dr M S DEEPA

DATE:03/08/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Anterior cruciate ligament (ACL) injury is one of the most common knee-related injuries, usually occurring in younger individuals during sports participation .Once ACL is disrupted, pain, effusion and atrophy are commonly observable and cause functional disability. Because of the functional limitations, athletic participation is severely restricted. Patients with anterior cruciate ligament (ACL) injury have a high risk of developing PTOA(Post Traumatic Osteo Arthritis).Knowledge of the risk factors that lead to ACL tears can help to correctly diagnose knee injuries and is important to the development of prevention strategies for knee osteoarthritis. The signs and symptoms of ACL injuries  are much similar with that of Janumarmaabhigatha.

                In the present study an attempt is made to find out an effective treatment protocol for  the management of partial tears of Anterior Cruciate Ligament  of knee joint. As a part of literary work, modern and ayurvedic views about the disease, its management and a detailed review of drugs used in the study were compiled.The study design of the present work was pre and post test without control, in which 30 subjects of partial tears of Anterior Cruciate Ligament  of knee joint was selected according to inclusion and exclusion criteria. The patients were treated with Lepana,,bandhana, Achasnehapana, abhyanga and ushmasweda , virechana ,Ekangadhara, mathravasthi and shashtikasalipinda swedam, ksheeravasthi . Along with this internal medicines were given for the patients. The internal medicines include Musthadi  marma kashayam, Laksha guggulu and Gandha thailam. In this study the findings were observed before treatment  0^th day and 46^th  day of treatment. The results are tabulated using the medical statistics. The results revealed that the protocol helps in relieving pain, swelling and restricted movement of knee joint to a certain extent. This enables the patient to resume day today activities and the result is statistically significant.

 INTIMATION FOR BODHIKA SEMINAR - 27/07/2022

DEPARTMENTS OF KAUMARA BHRITYA AND RASA SHASTRA & BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ALKA CHOUHAN

THESIS TITLE:EFFECT OF VYAGHRI HARITAKI LEHYA IN CHRONIC TONSILLTIS IN CHILDREN OF THE AGE GROUP 

3-12YEARS

NAME OF GUIDE: Dr MINI S MURALIDHAR

NAME OF CO-GUIDE: Dr SAREENA  K

DATE:27/07/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Respiratory infections are major cause of morbidity and mortality in children. Chronic tonsillitis is the second most common prevalent disease in paediatric age group from 5-15 years. Tonsillitis is the aggravation of the tonsils two oval formed cushions at the rear of the throat which are resistant frameworks first line of safeguard. Tonsils and adenoids are the body’s first line of defence at the oro-pharyngeal gateway. Recurrent attack of chronic tonsillitis makes the disease chronic and vulnerable for infections diseases. It is estimated that 15% of all visits to family doctors are because of chronic tonsillitis. In Ayurveda, tonsillitis can be correlated with Tundikeri. The diseases of Talu(Palate ) and kantha ( Throat ) , both of which are the ayatanas (eshtablishment ) of mukharoga (Diseases of Mouth).Tundikeri one among the urdhvajatrugata roga; mentioned in talugata roga (disease of palate) as well as Kanthagata roga (diseases of throat). Ayurvedic acharyas have given detailed elaboration regarding the various etiological factors, prodromal symptoms, presenting symptoms, various signs, prognosis and the various treatment modalities to be adopted in the treatment of Tundikeri. Vyaghri Haritaki lehya, a classical formulation in Bhaishajya Ratnavali, is an Avaleha (electuary), palatable and can be licked by children having soothing effect on throat. Vyaghri Haritaki lehya possesses other properties like Deepana, Pachana, Anulomana, Raktasodhana, Shothahara (Anti-inflammatory), Kapha-vatashamaka, Balya and Rasayana. 20 children were screened and selected for the trial from OPD of Dept. of Kaumarabhrithya, Govt. Ayurveda College hospital for women and children, Poojapura, Thiruvanvanthapuram. Internal administration of Vyaghri haritaki lehya in a doses are 5gm for children between 3 to 6 years and 10gm for children between 7 to 12 years with honey as adjuvant, for a period of 60 days were given. Follow up done after a period of 30 days. Lab investigations and clinical assessment were taken before and after interventional period and after the follow up. Data was analyzed by Wilcoxon signed rank test and the results proven that the study was statistically significant P value <0.05.