INTIMATION FOR BODHIKA SEMINAR - 03/08/2022

DEPARTMENTS OF SALYA TANTRA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr M T AMRUTHA

THESIS TITLE: EFFECT OF SELECTED  TREATMENT

 PROTOCOL IN  THE MANAGEMENT OF PARTIAL 

TEAR OF ANTERIOR CRUCIATE LIGAMENT OF 

KNEE JOINT

NAME OF GUIDE: Dr C S SIVAKUMAR

NAME OF CO-GUIDE: Dr M S DEEPA

DATE:03/08/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Anterior cruciate ligament (ACL) injury is one of the most common knee-related injuries, usually occurring in younger individuals during sports participation .Once ACL is disrupted, pain, effusion and atrophy are commonly observable and cause functional disability. Because of the functional limitations, athletic participation is severely restricted. Patients with anterior cruciate ligament (ACL) injury have a high risk of developing PTOA(Post Traumatic Osteo Arthritis).Knowledge of the risk factors that lead to ACL tears can help to correctly diagnose knee injuries and is important to the development of prevention strategies for knee osteoarthritis. The signs and symptoms of ACL injuries  are much similar with that of Janumarmaabhigatha.

                In the present study an attempt is made to find out an effective treatment protocol for  the management of partial tears of Anterior Cruciate Ligament  of knee joint. As a part of literary work, modern and ayurvedic views about the disease, its management and a detailed review of drugs used in the study were compiled.The study design of the present work was pre and post test without control, in which 30 subjects of partial tears of Anterior Cruciate Ligament  of knee joint was selected according to inclusion and exclusion criteria. The patients were treated with Lepana,,bandhana, Achasnehapana, abhyanga and ushmasweda , virechana ,Ekangadhara, mathravasthi and shashtikasalipinda swedam, ksheeravasthi . Along with this internal medicines were given for the patients. The internal medicines include Musthadi  marma kashayam, Laksha guggulu and Gandha thailam. In this study the findings were observed before treatment  0^th day and 46^th  day of treatment. The results are tabulated using the medical statistics. The results revealed that the protocol helps in relieving pain, swelling and restricted movement of knee joint to a certain extent. This enables the patient to resume day today activities and the result is statistically significant.

 INTIMATION FOR BODHIKA SEMINAR - 27/07/2022

DEPARTMENTS OF KAUMARA BHRITYA AND RASA SHASTRA & BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ALKA CHOUHAN

THESIS TITLE:EFFECT OF VYAGHRI HARITAKI LEHYA IN CHRONIC TONSILLTIS IN CHILDREN OF THE AGE GROUP 

3-12YEARS

NAME OF GUIDE: Dr MINI S MURALIDHAR

NAME OF CO-GUIDE: Dr SAREENA  K

DATE:27/07/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Respiratory infections are major cause of morbidity and mortality in children. Chronic tonsillitis is the second most common prevalent disease in paediatric age group from 5-15 years. Tonsillitis is the aggravation of the tonsils two oval formed cushions at the rear of the throat which are resistant frameworks first line of safeguard. Tonsils and adenoids are the body’s first line of defence at the oro-pharyngeal gateway. Recurrent attack of chronic tonsillitis makes the disease chronic and vulnerable for infections diseases. It is estimated that 15% of all visits to family doctors are because of chronic tonsillitis. In Ayurveda, tonsillitis can be correlated with Tundikeri. The diseases of Talu(Palate ) and kantha ( Throat ) , both of which are the ayatanas (eshtablishment ) of mukharoga (Diseases of Mouth).Tundikeri one among the urdhvajatrugata roga; mentioned in talugata roga (disease of palate) as well as Kanthagata roga (diseases of throat). Ayurvedic acharyas have given detailed elaboration regarding the various etiological factors, prodromal symptoms, presenting symptoms, various signs, prognosis and the various treatment modalities to be adopted in the treatment of Tundikeri. Vyaghri Haritaki lehya, a classical formulation in Bhaishajya Ratnavali, is an Avaleha (electuary), palatable and can be licked by children having soothing effect on throat. Vyaghri Haritaki lehya possesses other properties like Deepana, Pachana, Anulomana, Raktasodhana, Shothahara (Anti-inflammatory), Kapha-vatashamaka, Balya and Rasayana. 20 children were screened and selected for the trial from OPD of Dept. of Kaumarabhrithya, Govt. Ayurveda College hospital for women and children, Poojapura, Thiruvanvanthapuram. Internal administration of Vyaghri haritaki lehya in a doses are 5gm for children between 3 to 6 years and 10gm for children between 7 to 12 years with honey as adjuvant, for a period of 60 days were given. Follow up done after a period of 30 days. Lab investigations and clinical assessment were taken before and after interventional period and after the follow up. Data was analyzed by Wilcoxon signed rank test and the results proven that the study was statistically significant P value <0.05.

 INTIMATION FOR BODHIKA SEMINAR - 20/07/2022

DEPARTMENTS OF DRAVYA GUNA VIJNANAM

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr MADONNA PHILIPOSE

THESIS TITLE: Efficacy of patoladi yogam as add on medication  in Type 2 Diabetes mellitus subjects  on metformin monotherapy – A randomized placebo controlled clinical trial

NAME OF GUIDE: Dr M S DEEPA

DATE:20/07/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia due to impaired insulin  secretion or utilization or both in human body. Diabetes mellitus and its  associated complications have been posing a major threat to the health status of a large population in both developing and developed countries since decades. The major types of diabetes mellitus are type 1 and type 2.Type 2 diabetes mellitus also known as non-insulin dependent diabetes, results from body’s inefficient use of insulin and affects the vast majority. The prevalence of diabetes in adults of 20-79 years  in India is 8.3% . In Ayurveda diabetes can be considered as prameha symptomatically. In the Ayurvedic classics ,a large number of herbal preparations are mentioned in the contexts pertaining to treatment of prameha ,many of which are still left unexplored and scientifically validate .The study drug patoladi yogam is a polyherbal formulation mentioned in one of the classical Ayurveda texts, Ashtanga hridaya in the chapter of treatment of prameha. The constituent herbs of the formulation are patola (Trichosanthes dioica Roxb) ,nimba(Azadirachta indica A.Juss),amalaki(Embilica officinalis Gaertn) and amrutha(Tinospora cordifolia Miers) having  tridosahara,kandughna,rasayana and pramehaghna properties respectively, that can be effective in mitigating the longterm complications associated with DM. Preliminary phytochemical analysis of the study drug was  done. The study is  interventional RCT . Both male and female participants of age group 25-60 years  with FBS level from 126-200 mg/dl, PPBS level from 200-250 mg/dl ,HbA1c level from 6.5%- 8.5%  taking metformin monotherapy, attending OPD of Govt.Ayurveda College, Thiruvananthapuram were selected   for the study. Participants with major systemic illness and complications were excluded. The study population was divided into two groups as experimental and control groups. The study drug patoladi yoga was powdered and potentiated in its  own decoction and made into 500 mg capsules. It was dispensed to the patients of experimental group  .The control group was given similar capsules of  placebo.  The participants of both the group  were advised to take 2 capsules each thrice daily before food for a period of 90 days.  The required laboratory investigations FBS,PPBS,HbA1c were done before and after the study period. The collected data after completion of trial will be subjected to statistical analysis using appropriate statistical techniques. Results will be drawn ,summarized and conclusions will be made.

 INTIMATION FOR BODHIKA SEMINAR - 13/07/2022

DEPARTMENTS OF AGADA TANTRA & RASA SHASTRA AND BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ANU MARIAM VARGHESE

THESIS TITLE:NEPHROPROTECTIVE EFFECT OF SUGANDHADI AGADA ON CISPLATIN INDUCED NEPHROTOXICITY IN MALE WISTAR RATS

NAME OF GUIDE: Dr JAYASREE M N

NAME OF CO-GUIDE: Dr SURAJ K

DATE:13/07/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

In the current scenario drug induced toxicity is a major headache to the health sector limiting the usefulness of widely used agents. The development of severe, drug related complications may require premature drug withdrawal or dose reduction. In some cases, toxicity occurs in majority of treated individuals because of the nature of the drug (e.g. cytotoxic agents used for cancer-chemotherapy). Cisplatin (Cis-diamminedichloroplatinum II) is one of the most widely used and highly effective chemotherapeutic agents. Its treatment has been linked to various toxic side effects including nephrotoxicity, myelosuppression, cardiotoxicity etc. Acute kidney injury occurs in 21-31.55% patients receiving cisplatin-based chemotherapy. Now worldwide, 850 million people are estimated to have kidney diseases from various causes and are the 10^th fastest growing cause of death. In this study we are aiming to provide relief to patients on cisplatin medication. For this purpose, Sugandhadi agada, a formulation mentioned under mandali visha prakarana of Ashtanga Hridaya, Uttarasthana Sarpavisha Prathishedha is selected. Mandali Visha can be correlated to Viper envenomation by its signs and symptoms, the mode of death etc. In Viper envenomation, the mainly affected system is circulatory system and death may be due to acute renal failure. Therefore, the treatment will definitely target the circulatory and renal system. Hence, this work aims to study the nephroprotective effect of the formulation mentioned under mandali visha prakarana to tackle the aftereffects of xenobiotics causing nephrotoxicity. Physico-chemical analysis of the formulation was conducted at Department of Chemistry, Siddha Regional Research Institute, Poojappura Thiruvananthapuram and Sophisticated Test and Instrumentation Centre (STIC), CUSAT. The experimental study was conducted at Amala Cancer Research Center, Thrissur. Male wistar rats weighing 150-200g purchased from authentic breeding centers and were divided into 6 groups containing 6 animals each. The groups selected for the study are; normal, vehicle control, Cisplatin (7mg/ kg body wt.), Sugandhadi agada at high, therapeutic and low doses along with cisplatin. All the groups received their respective drugs for 14 days, except Cisplatin which was given on 10th day. Changes in the animals observed and animal sacrificed at the end of 14th day. Changes in hematological parameters- serum urea, serum creatinine, serum uric acid, serum alkaline phosphatase, serum bilirubin were assessed after collecting blood through heart puncture. Enzymatic activities along with histopathological changes in kidney were also evaluated. Results were statistically analyzed by one way ANOVA, followed by Tukey’s multiple comparison tests as post-hoc test. The overall result suggests that the Sugandhadi agada has no significant nephroprotective effects against cisplatin induced nephrotoxicity in this study.

  INTIMATION FOR BODHIKA SEMINAR - 06/07/2022

DEPARTMENTS OF SWASTHA VRITTA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr VEENA VIJAYAN

THESIS TITLE:

PREVALANCE OF ADHOVEGADHARANA AND ITS ILL EFFECTS AMONG WORKING WOMEN IN THIRUVANANTHAPURAM CITY                    

NAME OF GUIDE: Dr SREERAJ S.K 

NAME OF CO-GUIDE; Dr SMITHA MARY SHINE

DATE:06/07/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Vegas are natural urges and are usually spontaneous in nature. They are inevitable for the maintenance of proper health. Tendency to suppress natural urges are common among working women. Especially suppression of urine, feaces and flatus are common in them due to the social circumstances and their busy life schedule. According to Ayurvedaadhovegadharana can cause many symptoms such as siroruja ,klama etc. Suppression of urine can lead to urinary tract infection ,which is the second most common bacterial infection in the world. Suppression of urge to defecate can cause Constipation. Suppression of flatus can lead to the formation of diverticula. Working women due to lack of time , long working hours   using  unhygienic toilet etc are more susceptible for the suppression of natural urges, The study was  conducted to find out the habit of suppression of adhovegas and its ill effects among them. For the study 300 working women from various institution  in Thiruvananthapuram city were  selected by cluster sampling and were given semi structured questionnaire which is pretested by the experts in this field . With the help of this prevalence adhovegadharanaand its ill effects will be elicited. The analysis of preliminary data , personal history ,  suppression habits and ill effects has brought out the prevalence of adlogavegadharana and its ill effects and the significance of association between them . The result obtained in the study were analysed by Chi-square test. 84.3% of the women were having the habit of suppression of one or more adhogavega . Among the 3 adhogavega mutra is the most commonly suppressed one. The ill effects like head ache, muscle cramps,body ache are highly prevalent among working women who were having the habit of suppression of adhogavega.