INTIMATION FOR BODHIKA SEMINAR - 14/3/2022

DEPARTMENT OF RASA SHASTRA AND BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE : Dr ANITHA M

   

THESIS TOPIC: ACUTE AND SUBACUTE TOXICITY 

OF SURYAPRABHA GULIKA IN WISTARBALBINO RATS

 

NAME OF CO GUIDE:Dr S ANAND

NAME OF CO GUIDE: Dr T D BABU

DATE: 14/3/2022

TIME: 2:00-4:00 PM

VENUE: MICROSOFT TEAMS

ABSTRACT

Rasasastra is the branch of Ayurveda deals with processes by which various metals, minerals and other substances including mercury are purified, combined with suitable herbs in appropriate ratio in an attempt to treat illness. From 5th century onwards, the advancement rasasastra and use of metals or minerals opened a new frontiers for ayurvedic pharmacology and pharmaco-therapeutics. But the toxicity of traditional ayurvedic medicines with metalomineral combinations is a matter of concern among ayurvedic practitioners due to the presence of heavy metals. Rasaushadhis irrespective of its lesser therapeutic doses, enhancement of action of other ingredients in the formulation, quicker action and wide range of therapeutic purposes are always questioned for its safety profile. Suryaprabha gulika is a traditional ayurvedic formulation mentioned in Sahasrayogam containing both herbal and mineral ingredients and is indicated for the management of fever and upper respiratory tract infections. Though it is available in our market, there is no scientific data available regarding the therapeutic index of the formulation. This study aims to evaluate the acute and subacute toxicity of the formulation in wistar albino rats of either sex. Animals will be sacrificed at the end of the study. Physiological, haematological, biochemical and histopathlogical parameters will be assessed thereafter. Datas obtained after the study will be statistically analysed using appropriate modes. 

NAME  OF  SECOND PRESENTEE : Dr ANJANA S VIJAYAN

THESIS TOPIC: EFFECT OF KASEESADI VAGINAL 

SUPPOSITORY IN VULVO VAGINAL CANDIDIASIS

 

NAME OF CO GUIDE:Dr R RAJAM

NAME OF CO GUIDE: Dr ASHA SHREEDHAR

DATE: 14/3/2022

TIME: 2:00-4:00 PM

VENUE: MICROSOFT TEAMS

ABSTRACT

Vulvovaginal candidiasis is most prevalent vaginitis produced by a ubiquitous, air born, gram positive fungus. More than 90%of cases are caused by Candida albicans. When the vaginal ecosystem has disturbed Candida albicans can become an opportunistic pathogen. Hormonal factors, depressed cell mediated immunity, antibiotic use are three most important factors that alter the vaginal ecosystem. Cottage cheese like vaginal discharge,vulval itching, excoriation,dyspareunia and dysuria are the major symptoms .About 8% of women are suffering with recurrent vaginal candidiasis. Its complications are physical and mental stress, pelvic inflammatory disease and Infertility. Slaishmiki yoni vyapath appears with Pandu Pichila Yonisrava,Yoni kandu,alpa vedana and it can be correlated with symptoms of vulvovaginal candidiasis . Considering conventional ayurvedic treatments like yoni kshalanam,varthi etc Kaseesadi churna yoga mentioned in ashtanga hrudayam, uthara sthanam guhya roga prathishedha adhyaya under slaishmiki yoni vyapath chikitsa was modified into vaginal suppository form to make it more convenient & to get more acceptances in modern era. The yoga contains Kaseesa,Thriphala (Hareethaki, Vibheetaki and Amalaki), Kankshi, amrasthi, Jambu asthi and Dhathaki It is an interventional pre post study with sample size 26.The study is intended to evaluate the effect of Kaseesadi vaginal suppository in vulvovaginal candidiasis and to do the physico chemical parameters of the Kaseesadi vaginal suppository .The study was conducted at OPD of Prasuti Tanthra and Stree roga and Department of Rasasasthra &Bhaishajya kalpana, Government Ayurveda College,Thiruvananthapuram among the 20-50 years old married female participants with vaginal Candida albicans infection and having moderate or mild degree of infection on Wet Mount Test . A detailed history of subject will be taken by case proforma. Diagnosis confirmed by Wet Mount test. Self administration of Single Kaseesadi vaginal suppository at bed time for continues 7 days from 8th day of menstruation with an applicator. This will be repeated for 3 consecutive cycles. The Outcome variables will be checked with scores of Wet Mount test and score of signs and symptoms will be analysed before and after treatment. The results will be analysed through statistical analysis.