INTIMATION FOR BODHIKA SEMINAR - 15/06/2022

DEPARTMENT  OF  RASA SHASTRA AND BHAISHAJYA KALPANA

GOVT. AYURVEDA COLLEGE, THIRUVANANTHAPURAM

NAME  OF  FIRST PRESENTEE: Dr ANJU ELSA ROY

THESIS TITLE: COMBINED EFFECT OF SHILAJITWADI

 YOGA AND KALLURVANCHYADI KASHAYA IN UROLITHIASIS                                                                               

NAME OF GUIDE: Dr SREENI T V

DATE:15/06/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS 

ABSTRACT

Urolithiasis is one of the common disorders of urinary system with a prevalence of 4-20%. Prevalence more in males than female, the problem of stone formation is considered as a medical challenge due to multifactorial aetiology and high rate of recurrence. In modern science treatment modalities includes non-steroidal anti-inflammatory drugs, anti-emetics, and diuretics, in later stages minimum invasive procedures like ESWL, URS, PCNL was done. In Ayurveda urolithiasis comes under Mootrashmari, it was well explained by all acharyas. As per Ayurveda concept  Mootrashmari can treat with Oushadas at initial stage, in later stages can treat with Sastras. The study aims to clinically evaluate combined effect of Shilajathwadi Yoga and Kallurvanhyadi Kashaya in urolithiasis. Shilajathwadi yoga mentioned in Astanga Sangraha Utharasthana Vishopayogika Adhyaya, contains Sudha Shilajathu and Sudha Vatsanabha, for the convenience of the patient it was converted to capsules. Kallurvanchyadi kashaya mentioned in Sahasrayoga kashaya prakarana . After the preparation of the trial drug physicochemical analysis was done. The study was carried out as a single group pre post interventional trail with a sample size of 20. Patients were selected from OPD, Department of Rasasasthra and Bhaishajya Kalpana, Govt. Ayurveda college hospital,  Thiruvananthapuram. The study subjects were administered 500 mg Shilajathwadi Yoga capsule and 48 ml of Kallurvanchyadi Kashaya twice daily before food for 45 days. Assessment was done based on the change in size of stone by Ultrasonography-abdomen and change in score of signs and symptoms before and after treatment. The trial drug was effective in reducing pain, burning micturition, dysuria, renal angle tenderness, number and size of stone with a significance level of  1% (p < 0.01) and haematuria, and pus cells with a significance level of 5% (p < 0.05).

NAME  OF  SECOND PRESENTEE: Dr JAMALIYA  V M

THESIS TITLE: INVITRO ANTI MICROBIAL ACTIVITY

 OF JWARANKUSA RASA                                                                 

NAME OF GUIDE: Dr R RAJAM

DATE:15/06/2022

TIME: 2:00-4:00 PM

VENUE: HYBRID / MICROSOFT TEAMS

ABSTRACT

 Rasayogas in Ayurveda have a wide range of therapeutic utility since they are fast acting even in smaller doses.Acharya Charaka mentioned, Jwara is the foremost of all diseases, so it need a special attention. Wide variety of Rasayogas were mentioned in classics for Jwara. Jwarankusa rasa is a well-known herbo-mineral formulation specially indicated for vishama jwara and it is mentioned in Bhaishajya ratnavali Jwara chikitsa. As per Susrutha “Agantu cha anubandho hi prayasho vishama jware” and these agantu karana could be considered as micro organisms. So a study has been conducted to assess the anti-microbial activity of Jwarankusa rasa in E. coli, Salmonella paratyphi,Pseudomonas aeruginosa, Enterococcus fecalis.

       Antimicrobial activity of Jwarankusa rasa has been studied on these organisms by Agar well diffusion method. Since it is a herbo-mineral formulation, one combination of non-herbal ingredients and another combination of ethanolic extracts of herbal ingredients of Jwarankusa rasa were separately prepared and in-vitro anti-microbial study was done. It was found that Jwarankusa rasa had developed Zone of Inhibition in Ecoli,Pseudomonas aeruginosa, Salmonella paratyphi and no Zone of Inhibition in Enterococcus fecalis. The combination made by the ethanolic extracts of herbal ingredients of the formulation hasn’t developed Zone of inhibition in any of the organisms.The results of experimental study were statistically analyzed using one sample z test. . It was found to be statistically significant in Ecoli and Pseudomonas aeruginosa only.